Publications                                                                      PubMed

• Basant A, Lekomtsev S, Tse YC, Zhang D, Longhini KM, Petronczki M, Glotzer M. (2015) Aurora B Kinase Promotes Cytokinesis by Inducing Centralspindlin Oligomers that Associate with the Plasma Membrane. Dev Cell. 2015 Apr 20;33(2):204-15. doi: 10.1016/j.devcel.2015.03.015. PMID: 25898168
• White EA, Raghuraman H, Perozo E, Glotzer M (2013). Binding of the CYK-4 Subunit of the Centralspindlin Complex Induces a Large Scale Conformational Change in the Kinesin Subunit. J Biol Chem. 2013 288:19785-95. PMID: 23720745
• Glotzer M (2013). Cytokinesis: centralspindlin moonlights as a membrane anchor. Curr Biol. 2013 Feb 18;23(4):R145-7. doi: 10.1016/j.cub.2013.01.006. PMID: 23428321
• White, E. A., and Glotzer, M. (2012). Centralspindlin: At the heart of cytokinesis. Cytoskeleton (Hoboken) 69, 882–892. PMID: 22927365
• Tse, Y. C., Werner, M., Longhini, K. M., Labbé, J.-C., Goldstein, B., and Glotzer, M. (2012). RhoA activation during polarization and cytokinesis of the early C. elegans embryo are differentially dependent on NOP-1 and CYK-4. Mol Biol Cell 23, 4020–4031. PMID: 22918944
• Strickland D, Lin Y, Wagner E, Hope CM, Zayner J, Antoniou C, Sosnick TR, Weiss EL, Glotzer M. (2012) TULIPs: tunable, light-controlled interacting protein tags for cell biology. Nat Methods. 2012 Mar 4. doi: 10.1038/nmeth.1904. PMID: 22388287
• Loria A, Longhini KM, Glotzer M. (2012) The RhoGAP Domain of CYK-4 Has an Essential Role in RhoA Activation. Curr Biol. Feb 7;22(3):213-9. Epub 2012 Jan 5. PMID: 22226748
• Tse YC, Piekny A, Glotzer M Anillin promotes astral microtubule-directed cortical myosin polarization. Mol Biol Cell 2011 Sep;22(17):3165-75. Epub 2011 Jul 7. PMID: 2173768.

  • Regulation of cortical contractility and spindle positioning by the protein phosphatase 6 PPH-6 in one-cell stage C. elegans embryos.Development 2010 Jan;137(2):237-47. PMID: 20040490
  • Clustering of Centralspindlin Is Essential for Its Accumulation to the Central Spindle and the Midbody.Curr Biol. 2009 Dec 2. PMID: 19962307
  • Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation. PLoS Biol. 2009 May 5;7(5):e1000110. Epub 2009 May 26. // PubMed PMID: 19468300; PubMed Central PMCID: PMC2680334.
  • The 3Ms of central spindle assembly: microtubules, motors and MAPs. Nat Rev Mol Cell Biol. 2009 Jan;10(1):9-20. PubMed PMID: 19197328.
  • Cytokinesis: GAP gap. Curr Biol. 2009 Feb 24;19(4):R162-5. PubMed PMID: 19243691.
  • Single cells (put a ring on it). Genes Dev. 2009 Apr 15;23(8):896-901. PubMed PMID: 19390083.
  • Control of cortical contractility during cytokinesis. Biochem Soc Trans. 2008 Jun;36(Pt 3):371-7. PubMed PMID: 18481961.
  • Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis. EMBO J. 2008 Jul 9;27(13):1791-803. Epub 2008 May 29. PubMed PMID: 18511905; PubMed Central PMCID: PMC2486418.
  • Anillin is a scaffold protein that links RhoA, actin, and myosin during cytokinesis. Curr Biol. 2008 Jan 8;18(1):30-6. Epub 2007 Dec 27. PubMed PMID: 18158243.
  • Developmental regulation of central spindle assembly and cytokinesis during vertebrate embryogenesis. Curr Biol. 2008 Jan 22;18(2):116-23. PubMed PMID: 18207743.
  • Polo-like kinase 1 triggers the initiation of cytokinesis in human cells by promoting recruitment of the RhoGEF Ect2 to the central spindle. Dev Cell. 2007 May;12(5):713-25. PubMed PMID: 17488623.
  • Cooperative assembly of CYK-4/MgcRacGAP and ZEN-4/MKLP1 to form the centralspindlin complex. Mol Biol Cell. 2007 Dec;18(12):4992-5003. Epub 2007 Oct 17. PubMed PMID: 17942600; PubMed Central PMCID: PMC2096608.
  • Astral signals spatially bias cortical myosin recruitment to break symmetry and promote cytokinesis. Curr Biol. 2007 Aug 7;17(15):1286-97. PubMed PMID: 17669650; PubMed Central PMCID: PMC1978103.
  • Structural analysis of the ZEN-4/CeMKLP1 motor domain and its interaction with microtubules. J Struct Biol. 2006 Jan;153(1):73-84. PubMed PMID: 16361109.
  • The molecular requirements for cytokinesis. Science. 2005 Mar 18;307(5716):1735-9. PubMed PMID: 15774750.
  • Cytokinesis: welcome to the Rho zone. Trends Cell Biol. 2005 Dec;15(12):651-8. Epub 2005 Oct 21. PubMed PMID: 16243528.
  • An ECT2-centralspindlin complex regulates the localization and function of RhoA. J Cell Biol. 2005 Aug 15;170(4):571-82. PubMed PMID: 16103226; PubMed Central PMCID: PMC2171506.
  • Phosphorylation of ZEN-4/MKLP1 by aurora B regulates completion of cytokinesis. Curr Biol. 2005 Apr 26;15(8):778-86. PubMed PMID: 15854913.
  • Comparative analysis of cytokinesis in budding yeast, fission yeast and animal cells. Curr Biol. 2004 Sep 21;14(18):R806-18. PubMed PMID: 15380095.
  • Cleavage furrow positioning. J Cell Biol. 2004 Feb 2;164(3):347-51. PubMed PMID: 14757750; PubMed Central PMCID: PMC2172245.
  • Cell cycle regulation of central spindle assembly. Nature. 2004 Aug 19;430(7002):908-13. Epub 2004 Jul 28. PubMed PMID: 15282614.
  • Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners. Mol Cell. 2003 Mar;11(3):571-5. PubMed PMID: 12667442.
  • Cytokinesis: progress on all fronts. Curr Opin Cell Biol. 2003 Dec;15(6):684-90. PubMed PMID: 14644192.
  • Cytokinesis: a logical GAP. Curr Biol. 2003 Aug 5;13(15):R589-91. PubMed PMID: 12906808.
  • CSC-1: a subunit of the Aurora B kinase complex that binds to the survivin-like protein BIR-1 and the incenp-like protein ICP-1. J Cell Biol. 2003 Apr 28;161(2):229-36. Epub 2003 Apr 21. PubMed PMID: 12707312; PubMed Central PMCID: PMC2172917.
  • The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo. J Cell Biol. 2002 Sep 2;158(5):901-14. Epub 2002 Sep 3. PubMed PMID: 12213836; PubMed Central PMCID: PMC2173158.
  • GTP binding induces filament assembly of a recombinant septin. Curr Biol. 2002 Oct 29;12(21):1858-63. PubMed PMID: 12419187.
  • Cytokinesis: regulated by destruction. Curr Biol. 2002 May 14;12(10):R344-6. PubMed PMID: 12015132.
  • The aurora B kinase AIR-2 regulates kinetochores during mitosis and is required for separation of homologous Chromosomes during meiosis. Curr Biol. 2002 May 14;12(10):798-812. PubMed PMID: 12015116.
  • A ubiquitin C-terminal hydrolase is required to maintain osmotic balance and execute actin-dependent processes in the early C. elegans embryo. J Cell Sci. 2002 Jun 1;115(Pt 11):2293-302. PubMed PMID: 12006614.
  • Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity. Dev Cell. 2002 Jan;2(1):41-54. PubMed PMID: 11782313.
  • Mammalian septins nomenclature. Mol Biol Cell. 2002 Dec;13(12):4111-3. PubMed PMID: 12475938; PubMed Central PMCID: PMC138619.
  • Separase is required for chromosome segregation during meiosis I in Caenorhabditis elegans. Curr Biol. 2001 Nov 27;11(23):1825-35. PubMed PMID: 11728305.
  • Animal cell cytokinesis. Annu Rev Cell Dev Biol. 2001;17:351-86. PubMed PMID: 11687493.
  • Incenp and an aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesis. Curr Biol. 2000 Oct 5;10(19):1172-81. PubMed PMID: 11050385.
  • CYK-4: A Rho family gtpase activating protein (GAP) required for central spindle formation and cytokinesis. J Cell Biol. 2000 Jun 26;149(7):1391-404. PubMed PMID: 10871280; PubMed Central PMCID: PMC2175131.
  • Depletion of syntaxins in the early Caenorhabditis elegans embryo reveals a role for membrane fusion events in cytokinesis. Curr Biol. 1999 Jul 15;9(14):738-45. PubMed PMID: 10421575.
  • Chromosome segregation: Samurai separation of Siamese sisters. Curr Biol. 1999 Jul 15;9(14):R531-4. PubMed PMID: 10421570.
  • Cytokinesis. Curr Biol. 1997 May 1;7(5):R274-6. PubMed PMID: 9115401.
  • Cytoplasmic flows localize injected oskar RNA in Drosophila oocytes. Curr Biol. 1997 May 1;7(5):326-37. PubMed PMID: 9115398.
  • CDK1 inactivation regulates anaphase spindle dynamics and cytokinesis in vivo. J Cell Biol. 1997 Jul 28;138(2):385-93. PubMed PMID: 9230080; PubMed Central PMCID: PMC2138195.
  • A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos. Curr Biol. 1997 Jan 1;7(1):12-23. PubMed PMID: 8999996.
  • The mechanism and control of cytokinesis. Curr Opin Cell Biol. 1997 Dec;9(6):815-23. PubMed PMID: 9425346.
  • Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates. Mol Biol Cell. 1996 Sep;7(9):1343-57. PubMed PMID: 8885231; PubMed Central PMCID: PMC275986.
  • Mitosis: don't get mad, get even. Curr Biol. 1996 Dec 1;6(12):1592-4. PubMed PMID: 8994822.
  • Cell cycle. The only way out of mitosis. Curr Biol. 1995 Sep 1;5(9):970-2. PubMed PMID: 8542285.
  • Cell polarity. The importance of being polar. Curr Biol. 1995 Oct 1;5(10):1102-5. PubMed PMID: 8548277.
  • Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor. Cell. 1993 Jul 2;73(7):1393-402. PubMed PMID: 8391932.
  • Cyclin is degraded by the ubiquitin pathway. Nature. 1991 Jan 10;349(6305):132-8. PubMed PMID: 1846030.
  • Cyclin activation of p34cdc2. Cell. 1990 Nov 30;63(5):1013-24. PubMed PMID: 2147872.
  • Cyclin is a component of maturation-promoting factor from Xenopus. Cell. 1990 Feb 9;60(3):487-94. PubMed PMID: 1967981.
  • Mitochondrial uncoupling protein from mouse brown fat. Molecular cloning, genetic mapping, and mRNA expression. J Biol Chem. 1985 Dec 25;260(30):16250-4. PubMed PMID: 2999153.
  • Glotzer Lab | Department of Molecular Genetics and Cell Biology | University of Chicago          © Michael Glotzer 2015