Research Projects

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Central Spindle Assembly

Spatial and Temporal Regulation of RhoA

Patterning of Cortical Myosin by Microtubules

Development of Novel Optogenetic Tools

Selected Publications

Strickland D, Lin Y, Wagner E, Hope CM, Zayner J, Antoniou C, Sosnick TR, Weiss EL, Glotzer M. (2012) TULIPs: tunable, light-controlled interacting protein tags for cell biology. Nat Methods. 2012 Mar 4. doi: 10.1038/nmeth.1904. PMID: 22388287

Loria A, Longhini KM, Glotzer M. (2012) The RhoGAP Domain of CYK-4 Has an Essential Role in RhoA Activation. Curr Biol. Feb 7;22(3):213-9. Epub 2012 Jan 5. PMID: 22226748

Tse YC, Piekny A, Glotzer M. Anillin promotes astral microtubule-directed cortical myosin polarization. Mol Biol Cell 2011 Sep;22(17):3165-75. Epub 2011 Jul 7. PMID: 2173768.

Hutterer A, Glotzer M, Mishima M. Clustering of Centralspindlin Is Essential for Its Accumulation to the Central Spindle and the Midbody. Curr Biol. 2009 Dec 2. PMID: 19962307

Cytokinesis: GAP gap. Curr Biol. 2009 Feb 24;19(4):R162-5. PubMed PMID: 19243691.

Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation. PLoS Biol. 2009

Cooperative assembly of CYK-4/MgcRacGAP and ZEN-4/MKLP1 to form the centralspindlin complex. Mol Biol Cell. 2007 

Astral signals spatially bias cortical myosin recruitment to break symmetry and promote cytokinesis. Curr Biol. 2007

Glotzer Lab | Department of Molecular Genetics and Cell Biology | University of Chicago          © Michael Glotzer 2013